Is breakfast really the most important meal for fat cells?

According to a recent article published in the Journal of Physiology, the habit of developing long-term breakfast affects the activity of genes involved in fat metabolism in our body, which in turn affects fat cells and increases their intake of sugar. This mechanism may reduce the risk of diabetes and cardiovascular disease.

Researchers from the University of Bath and the University of Nottingham have found that obese patients’ adipose tissue is relatively less sensitive to insulin than people with a thinner body. Importantly, this trend is positively correlated with people’s body fat levels.

In six weeks, the researchers tested 49 volunteers (29 healthy and 20 obese). Volunteers were divided into two groups, one group had breakfast before 11 o’clock and the other group remained hungry until noon. In the former group, volunteers were asked to consume at least 700 calories within two hours of waking up, while the fasting group was asked not to be able to consume any energy before noon.

During the experiment, the researchers examined the levels of metabolism, body composition, appetite response, and metabolic and cardiovascular health-related indicators in volunteers. In addition, they examined the expression levels of 44 fat-related genes in volunteers and studied the ability of adipocytes to respond to insulin-stimulated glucose intake.

According to Javier Gonzalez, lead author of the study, the study also reveals more clearly the characteristics of fat cells in response to daily diets, so we can more accurately target these intrinsic mechanisms for the treatment of obesity-related diseases. “Because participants are taking high-fiber breakfast, we can’t rule out the impact of breakfast content on fat cell metabolism, and further research is needed to address this issue.”